| 1 | Sicilia Nuoto SSD | Tempera Asya, Guglielmino Sofia, Serravalle Sofia, Schillaci Marta | 01'49''49 | 630 |  |  | |
50m 27.42 (27.42) 100m 54.49 (27.07) [54.49] 150m 1:22.35 (27.86) 200m 1:49.49 (27.14) [55.00] |
| 2 | Aquarius ASD - Trapani | Pace Alessandra, Pardo Eliana, Bianco Sara, Croce Eleonora | 01'53''93 | 560 | | | |
50m 27.59 (27.59) 100m 28.77 (01.18) [28.77] 150m 56.36 (27.59) 200m 1:24.71 (28.35) [55.94] 250m 1:53.93 (29.22) |
| 3 | Poseidon Sporting Club SSD - Catania | Ando' Martina, Bruno Rachele Agata, Bruno Silvia Agata, Cipriano Alessia | 01'54''09 | 557 | | | |
50m 28.15 (28.15) 100m 28.75 (00.60) [28.75] 150m 56.90 (28.15) 200m 1:25.53 (28.63) [56.78] 250m 1:54.09 (28.56) |
| 4 | Ulysse - Messina | Ficili Sofia Maria Pia, Fontana Giulia, Evangelista Diodato Michela, Pascucci Virginia | 01'54''13 | 557 | | | |
50m 27.90 (27.90) 100m 55.61 (27.71) [55.61] 150m 1:24.90 (29.29) 200m 1:54.13 (29.23) [58.52] |
| 5 | Power Team Messina | Cautela Gaia, Pianese Giada, Giacopello Manuela, Ganim Daniel | 01'56''40 | 525 | | | |
50m 28.98 (28.98) 100m 57.68 (28.70) [57.68] 150m 1:27.13 (29.45) 200m 1:56.40 (29.27) [58.72] |
| 6 | Altair Nuoto SSD - Catania | Gasparini Marzia Miriam, Pappalardo Annarita, Spoto Alessia, Pappalardo Erika | 01'56''66 | 521 | | | |
50m 29.53 (29.53) 100m 58.97 (29.44) [58.97] 150m 1:27.81 (28.84) 200m 1:56.66 (28.85) [57.69] |
| 7 | Synthesis Nuoto SSD - Aci Castello | Guerrera Stefania, D'Amico Alessia, Villa Asia, Scardino Giorgia | 01'58''30 | 500 | | | |
50m 30.13 (30.13) 100m 58.48 (28.35) [58.48] 150m 1:29.35 (30.87) 200m 1:58.30 (28.95) [59.82] |
| 8 | Polisportiva Nadir - Palermo | Ferrante Sara, Ventrella Giulia, Di Matteo Consilia, Giambalvo Francesca | 01'58''48 | 497 | | | |
50m 30.27 (30.27) 100m 59.81 (29.54) [59.81] 150m 1:29.19 (29.38) 200m 1:58.48 (29.29) [58.67] |
| 9 | La Meridiana Sport SSD - Catania | Colaianni Eleonora, Emanuele Fabiola, Ferro Chiara, Rizzo Giorgia | 01'59''19 | 489 | | | |
50m 29.91 (29.91) 100m 58.80 (28.89) [58.80] 150m 1:29.20 (30.40) 200m 1:59.19 (29.99) [1:00.39] |
| 10 | Ulysse - Messina | Muscolino Alessandra, Andronico Emanuela, Marche Sofia, Lenea Alexia | 02'00''38 | 474 | | | |
50m 30.91 (30.91) 100m 1:00.59 (29.68) [1:00.59] 150m 1:29.93 (29.34) 200m 2:00.38 (30.45) [59.79] |
| 11 | Synthesis Nuoto SSD - Aci Castello | Pennisi Claudia Giovanna, Giustolisi Monica, Allegra Denise, Guerrera Elena | 02'01''22 | 464 | | | |
50m 30.65 (30.65) 100m 1:00.72 (30.07) [1:00.72] 150m 1:32.35 (31.63) 200m 2:01.22 (28.87) [1:00.50] |
| 12 | Unime SSD - Messina | Cannizzaro Alessia, Bellantone Francesca, Pizzi Carlotta, Di Cara Federica | 02'02''92 | 445 | | | |
50m 29.31 (29.31) 100m 31.26 (01.95) [31.26] 150m 1:00.57 (29.31) 200m 1:32.57 (32.00) [1:01.31] 250m 2:02.92 (30.35) |
| 13 | La Meridiana Sport SSD - Catania | D'Ignoti Giada Francesca, Perkins Alyan Francesca, Rizzo Roberta, Celi Giorgia | 02'04''05 | 433 | | | |
50m 30.94 (30.94) 100m 1:01.45 (30.51) [1:01.45] 150m 1:32.07 (30.62) 200m 2:04.05 (31.98) [1:02.60] |
| 14 | Unime SSD - Messina | Soliera Alessandra, Giaconia Aurora, Perdichizzi Sofia, Zaccone Martina | 02'04''43 | 429 | | | |
50m 33.26 (33.26) 100m 1:03.55 (30.29) [1:03.55] 150m 1:33.90 (30.35) 200m 2:04.43 (30.53) [1:00.88] |
| 15 | Sun Club SSD - Siracusa | Veneziano Carola, Lo Bianco Giada, Caia Marialaura, Gambuzza Romana Lucia | 02'04''49 | 429 | | | |
50m 31.15 (31.15) 100m 31.24 (00.09) [31.24] 150m 1:02.39 (31.15) 200m 1:33.31 (30.92) [1:02.07] 250m 2:04.49 (31.18) |
| 16 | Poseidon Sporting Club SSD - Catania | Caliri Giulia, Messina Noemi Maria, Iudica Giuliana, Aiello Federica | 02'04''89 | 425 | | | |
50m 31.56 (31.56) 100m 1:02.42 (30.86) [1:02.42] 150m 1:34.56 (32.14) 200m 2:04.89 (30.33) [1:02.47] |
| 17 | Sun Club SSD - Siracusa | Minniti Virginia, Partescano Elena, Bramante Chiara Rita, Caia Martina Maria | 02'06''51 | 409 | | | |
50m 31.64 (31.64) 100m 31.76 (00.12) [31.76] 150m 1:03.40 (31.64) 200m 1:35.67 (32.27) [1:03.91] 250m 2:06.51 (30.84) |
| 18 | Altair Nuoto SSD - Catania | D'Arrigo Giulia, Bucolo Federica Natalia, Trovato Giada, Parisi Margherita | 02'09''59 | 380 | | | |
50m 32.73 (32.73) 100m 35.53 (02.80) [35.53] 150m 1:08.26 (32.73) 200m 1:39.86 (31.60) [1:04.33] 250m 2:09.59 (29.73) |
| 19 | Power Team Messina | Ganim Juli, Bonasera Martina, Russo Giorgia, Caselli Rita | 02'11''83 | 361 | | | |
50m 30.18 (30.18) 100m 31.45 (01.27) [31.45] 150m 1:01.63 (30.18) 200m 1:38.75 (37.12) [1:07.30] 250m 2:11.83 (33.08) |
| | Sicilia Nuoto SSD | Zappala' Alice, Recupero Giulia Virginia, Riolo Amelia, Franceschini Aurora | Squalificato | |
